VMworld US 2016 will be held in Las Vegas again at August 28-September 1. While the Moscone Center in San Francisco has been the favourite venue location since a few years, expansion and renovation of the Moscone Center prevents VMworld to be organized here in 2016.
The location will be the Mandalay Bay Hotel & Convention Center.
The renovation of Moscone is quite a project and will last a couple of years. So it is very well possible VMworld 2017 will be in Las Vegas as well.